Tiagabine

Written and reviewed by Dr Ibrahim Imam, Consultant Neurologist. Last reviewed .

Tiagabine. Tiagabine is a selective GABA reuptake inhibitor, It enhances the activity of GABA. Fully referenced neurology checklist.

Mode of action

  • Tiagabine is a selective GABA reuptake inhibitor
  • It enhances the activity of GABA

Indications

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Dosing

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Neurological side effects

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Systemic side effects

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Seizures aggravated by Tiagabine

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References

  1. Goldenberg MM. Overview of drugs used for epilepsy and seizures: etiology, diagnosis, and treatment. P T 2010; 35:392-415.
  2. Genton P, Guerrini R, Perucca E. Tiagabine in clinical practice. Epilepsia 2001; 42(Suppl 3):42-45. 
  3. Bauer J, Cooper-Mahkorn D. Tiagabine: efficacy and safety in partial seizures - current status. Neuropsychiatr Dis Treat 2008; 4:731-736.
  4. Schachter SC. A review of the antiepileptic drug tiagabine. Clin Neuropharmacol 1999; 22:312-317.
  5. Wolańczyk T, Grabowska-Grzyb A. Transient dystonias in three patients treated with tiagabine. Epilepsia 2001; 42:944-946.
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