Primidone

Written and reviewed by Dr Ibrahim Imam, Consultant Neurologist. Last reviewed .

Primidone. The mode of action of Primidone is unknown. Fully referenced neurology checklist.

Mode of action

  • The mode of action of Primidone is unknown

Indications

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Dosing

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Interactions with other AEDs

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Neuropsychiatric side effects

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Genitourinary side effects

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Systemic side effects

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References

  1. Goldenberg MM. Overview of drugs used for epilepsy and seizures: etiology, diagnosis, and treatment. P T 2010; 35:392-415. 
  2. Michelucci R, Pasini E, Riguzzi P, Andermann E, Kälviäinen R, Genton P. Myoclonus and seizures in progressive myoclonus epilepsies: pharmacology and therapeutic trials. Epileptic Disord 2016; 18:145-153.
  3. Johannessen SI, Landmark CJ. Antiepileptic drug interactions - principles and clinical implications. Curr Neuropharmacol 2010; 8:254-267.
  4. Benetello P, Furlanut M. Primidone-carbamazepine interaction: clinical consequences. Int J Clin Pharmacol Res 1987; 7:165-168.
  5. Kanner AM, Parra J, Frey M. The "forgotten" cross-tolerance between phenobarbital and primidone: it can prevent acute primidone-related toxicity. Epilepsia 2000; 41:1310-1314.
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