Investigational anti-seizure medications (ASMs)
Written and reviewed by Dr Ibrahim Imam, Consultant Neurologist. Last reviewed .
Investigational anti-seizure medications (ASMs). Allopregnanolone, Ganaxolone, SAGE-217, SAGE-547. Fully referenced neurology checklist.
Neurosteroids
- Allopregnanolone
- Ganaxolone
- SAGE-217
- SAGE-547
Other investigational AEDs
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References
- Bialer M, Johannessen SI, Levy RH, Perucca E, Tomson T, White HS. Progress report on new antiepileptic drugs: A summary of the Thirteenth Eilat Conference on New Antiepileptic Drugs and Devices (EILAT XIII). Epilepsia 2017; 58:181-221.
- Mula M. Investigational new drugs for focal epilepsy. Expert Opin Investig Drugs 2016; 25:1-5.
- Mudigoudar B, Weatherspoon S, Wheless JW. Emerging antiepileptic drugs for severe pediatric epilepsies. Semin Pediatr Neurol 2016; 23:167-179.
- Khalil A, Kovac S, Morris G, Walker MC. Carvacrol after status epilepticus (SE) prevents recurrent SE, early seizures, cell death, and cognitive decline. Epilepsia 2017; 58:263-273.
- Sperling MR, Klein P, Tsai J. Randomized, double-blind, placebo-controlled phase 2 study of ganaxolone as add-on therapy in adults with uncontrolled partial-onset seizures. Epilepsia 2017; 58:558-564.
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