Gabapentin
Written and reviewed by Dr Ibrahim Imam, Consultant Neurologist. Last reviewed .
Gabapentin. Gabapentin is a voltage-gated calcium channel modulator, It increases brain GABA synthesis. Fully referenced neurology checklist.
Mode of action
- Gabapentin is a voltage-gated calcium channel modulator
- It increases brain GABA synthesis
Indications
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Dosing
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Neurological side effects
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Genitourinary side effects
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Systemic side effects
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References
- Taylor CP. Mechanisms of action of gabapentin. Rev Neurol (Paris) 1997; 153(Suppl 1):S39-S45.
- Taylor CP, Gee NS, Su TZ, et al. A summary of mechanistic hypotheses of gabapentin pharmacology. Epilepsy Res 1998; 29:233-249.
- Al-Bachari S, Pulman J, Hutton JL, Marson AG. Gabapentin add-on for drug-resistant partial epilepsy. Cochrane Database Syst Rev 2013; 7:CD001415.
- McLean MJ. Gabapentin in the management of convulsive disorders. Epilepsia 1999; 40(Suppl 6):S39-S50.
- Goldenberg MM. Overview of drugs used for epilepsy and seizures: etiology, diagnosis, and treatment. P T 2010; 35:392-415.
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