Multiple sclerosis (MS): clinical red flags against diagnosis

Written and reviewed by Dr Ibrahim Imam, Consultant Neurologist. Last reviewed .

Multiple sclerosis (MS): clinical red flags against diagnosis. Hyperacute onset, Acute onset with rapid worsening. Fully referenced neurology checklist.

Onset red flags

  • Hyperacute onset
  • Acute onset with rapid worsening
  • Onset after the age of 50 years
  • Onset before the age of 11 years

Presentation red flags

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Symptom-specific red flags

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Sign-specific red flags

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Neuromuscular red flags

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References

  1. Solomon AJ, Arrambide G, Brownlee WJ, et al. Differential diagnosis of suspected multiple sclerosis: an updated consensus approach. Lancet Neurol 2023; 22:750-768.

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