PARK5 genetic Parkinson's disease (PD)

Written and reviewed by Dr Ibrahim Imam, Consultant Neurologist. Last reviewed .

PARK5 genetic Parkinson's disease (PD). This is possibly caused by mutations in the UCHL1 gene on chromosome 4p. Fully referenced neurology checklist.

Genetics

  • This is possibly caused by mutations in the UCHL1 gene on chromosome 4p
  • The transmission is autosomal dominant
  • Only one family has been reported

Clinical features

Locked: subscribe to see this section.

Treatment

Locked: subscribe to see this section.

References

  1. Leroy E, Boyer R, Auburger G, et al. The ubiquitin pathway in Parkinson's disease. Nature 1998; 395:451-452.
  2. Healy DG, Abou-Sleiman PM, Casas JP, et al. UCHL-1 is not a Parkinson's disease susceptibility gene. Ann Neurol 2006; 59:627-633.

Related checklists

Loading...