PARK13 genetic Parkinson's disease (PD)

Written and reviewed by Dr Ibrahim Imam, Consultant Neurologist. Last reviewed .

PARK13 genetic Parkinson's disease (PD). This is caused by mutations in the HTRA2 gene on chromosome 2p. Fully referenced neurology checklist.

Genetics

  • This is caused by mutations in the HTRA2 gene on chromosome 2p
  • The transmission is autosomal dominant

Clinical features

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Treatment

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References

  1. Strauss KM, Martins LM, Plun-Favreau H, et al. Loss of function mutations in the gene encoding Omi/HtrA2 in Parkinson's disease. Hum Mol Genet 2005; 14:2099-2111.

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