Taxanes induced neuropathy
Written and reviewed by Dr Ibrahim Imam, Consultant Neurologist. Last reviewed .
Taxanes induced neuropathy. Paclitaxel, Docetaxel, nab-Paclitaxel. Fully referenced neurology checklist.
Types of taxanes
- Paclitaxel
- Docetaxel
- nab-Paclitaxel
Mechanism of action
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Risks of neuropathy
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Clinical features of neuropathy
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Management
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Investigational preventative treatments
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References
- Rivera E, Cianfrocca M. Overview of neuropathy associated with taxanes for the treatment of metastatic breast cancer. Cancer Chemother Pharmacol 2015; 75:659-670.
- Kudlowitz D, Muggia F. Clinical features of taxane neuropathy. Anticancer Drugs 2014; 25:495-501.
- Song SJ, Min J, Suh SY, et al. Incidence of taxane-induced peripheral neuropathy receiving treatment and prescription patterns in patients with breast cancer. Support Care Cancer 2017; 25:2241-2248.
- Argyriou AA, Koltzenburg M, Polychronopoulos P, Papapetropoulos S, Kalofonos HP. Peripheral nerve damage associated with administration of taxanes in patients with cancer. Crit Rev Oncol Hematol 2008; 66:218-228.
- Nurgalieva Z, Xia R, Liu CC, Burau K, Hardy D, Du XL. Risk of chemotherapy-induced peripheral neuropathy in large population-based cohorts of elderly patients with breast, ovarian, and lung cancer. Am J Ther 2010; 17:148-158.
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