Autoimmune encephalitis: treatment

Written and reviewed by Dr Ibrahim Imam, Consultant Neurologist. Last reviewed .

Autoimmune encephalitis: treatment. Steroids, Immunosuppressants, Intravenous immunoglobulins (IVIg). Fully referenced neurology checklist.

First line immune treatments

  • Steroids
  • Immunosuppressants
  • Intravenous immunoglobulins (IVIg)
  • Plasma exchange

Second line immune treatments

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Proposed treatments for refractory cases

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Behavioural treatments

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Choreoathetosis treatments

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Dystonia treatments

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Insomnia treatments

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Psychiatric symptoms treatments

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Postural hypotension treatments

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Seizures treatments

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Spasticity treatments

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Sympathetic overactivity treatments

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Tics treatments

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Other treatments

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References

  1. Abboud H, Probasco JC, Irani S, et al. Autoimmune encephalitis: proposed best practice recommendations for diagnosis and acute management. JNNP 2021; 92:757-768.
  2. Abboud H, Probasco J, Irani SR, et al. Autoimmune encephalitis: proposed recommendations for symptomatic and long-term management. JNNP 2021; 92:897-907.
  3. Dinoto A, Ferrari S, Mariotto S. Treatment options in refractory autoimmune encephalitis. CNS Drugs 2022; 36:919-931.

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