Restless legs syndrome (RLS): differential diagnosis

Written and reviewed by Dr Ibrahim Imam, Consultant Neurologist. Last reviewed .

Restless legs syndrome (RLS): differential diagnosis. Nocturnal dystonia, Nocturnal leg cramps. Fully referenced neurology checklist.

Sleep-related differentials

  • Nocturnal dystonia
  • Nocturnal leg cramps
  • Periodic limb movements of sleep (PLMS)
  • Insomnia
  • REM sleep behaviour disorder (RBD)
  • Sleep apnoea
  • Sleep onset myoclonus

Other neurological differentials

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Systemic differentials

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References

  1. Byrne R, Sinha S, Chaudhuri KR. Restless legs syndrome: diagnosis and review of management options. Neuropsychiatr Dis Treat 2006; 2:155-164.
  2. Chahine LM, Chemali ZN. Restless legs syndrome: a review. CNS Spectr 2006; 11:511-520.

Related checklists

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