Neuromyelitis optica spectrum disorder (NMOSD): paraneoplastic

Written and reviewed by Dr Ibrahim Imam, Consultant Neurologist. Last reviewed .

Neuromyelitis optica spectrum disorder (NMOSD): paraneoplastic. Lung adenocarcinoma, Breast cancer. Fully referenced neurology checklist.

Commonest primary tumours

  • Lung adenocarcinoma
  • Breast cancer
  • Oesophageal adenocarcinoma

Other primary tumours

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Suggestive features

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References

  1. Beauchemin P, Iorio R, Traboulsee AL, Field T, Tinker AV, Carruthers RL. Paraneoplastic neuromyelitis optica spectrum disorder: a single center cohort description with two cases of histological validation. Mult Scler Relat Disord 2018; 20:37-42.
  2. Sepúlveda M, Sola-Valls N, Escudero D, et al. Clinical profile of patients with paraneoplastic neuromyelitis optica spectrum disorder and aquaporin-4 antibodies. Mult Scler 2018; 24:1753-1759.
  3. Sepúlveda M, Sola-Valls N, Escudero D, et al. Clinical profile of patients with paraneoplastic neuromyelitis optica spectrum disorder and aquaporin -4 antibodies. Mult Scler 2017; 1:1352458517731914.
  4. Deuel LM, Bunch ME. A case of paraneoplastic neuromyelitis optica associated with small cell lung carcinoma. J Neuroimmunol 2018; 316:130-132. 
  5. Wiener DC, Kaplan TB, Bravo-Iñiguez CE, Miller J, Berkowitz AL, Jaklitsch MT. Paraneoplastic neuromyelitis optica spectrum disorder as presentation of esophageal adenocarcinoma. Ann Thorac Surg 2018; 105:e133-e135.  
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