Multiple sclerosis (MS): magnetic resonance imaging (MRI): features

Written and reviewed by Dr Ibrahim Imam, Consultant Neurologist. Last reviewed .

Multiple sclerosis (MS): magnetic resonance imaging (MRI): features. Periventricular, Juxtacortical, Infratentorial. Fully referenced neurology checklist.

Typical locations of lesions

  • Periventricular
  • Juxtacortical
  • Infratentorial
  • Corpus callosum: undersurface
  • Spinal cord

Typical lesions

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Periventricular lesions

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Juxtacortical lesions

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Infratentorial lesions

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Central vein sign (CVS): characteristic features

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Central vein sign (CVS): other causes

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Cortical lesions: characteristic features

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Cortical lesions: pathological classification

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Paramagnetic rim lesions

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Other brain lesions features

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Spinal cord lesions

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Optic nerve lesions: characteristics

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Optic nerve lesions: differentials

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Choroid plexus markers

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Slowly expanding lesions (SELs)

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Acronym

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References

  1. Filippi M, Preziosa P, Banwell BL, et al. Assessment of lesions on magnetic resonance imaging in multiple sclerosis: practical guidelines. Brain 2019; pii: awz144 (Epub ahead of print).
  2. Palace J. Making the diagnosis of multiple sclerosis. JNNP 2001; 71(suppl II):ii3-ii8.
  3. Charil A, Yousry TA, Rovaris M. MRI and the diagnosis of multiple sclerosis: expanding the concept of “no better explanation”. Lancet Neurol 2006; 5:841-852.
  4. Sati P, Oh J, Constable RT, et al; NAIMS Cooperative. The central vein sign and its clinical evaluation for the diagnosis of multiple sclerosis: a consensus statement from the North American Imaging in Multiple Sclerosis Cooperative. Nat Rev Neurol 2016; 12:714-722.
  5. Samaraweera APR, Falah Y, Pitiot A, Dineen RA, Morgan PS, Evangelou N. The MRI central vein marker; differentiating PPMS from RRMS and ischemic SVD. Neurol Neuroimmunol Neuroinflamm 2018; 5:e496.
  6. And 22 more. Subscribe to see the full list

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