Limbic predominant age related TDP-43 encephalopathy (LATE): diagnostic criteria
Written and reviewed by Dr Ibrahim Imam, Consultant Neurologist. Last reviewed .
Limbic predominant age related TDP-43 encephalopathy (LATE): diagnostic criteria. Age of onset >75 years. Fully referenced neurology checklist.
Clinical criteria
- Age of onset >75 years
- A primary amnestic syndrome with temporo-limbic memory loss
- There may be mild semantic memory impairment
- Sparing of other cognitive functions until later
- It runs an indolent course over >2 years
Radiological criteria
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Supportive tests
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