Hereditary spastic paraplegia type 37 (SPG37)

Written and reviewed by Dr Ibrahim Imam, Consultant Neurologist. Last reviewed .

Hereditary spastic paraplegia type 37 (SPG37). This is caused by mutations in chromosome 8p. Fully referenced neurology checklist.

Genetics

  • This is caused by mutations in chromosome 8p
  • The transmission is autosomal dominant

Clinical features

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Magnetic resonance imaging (MRI) brain

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References

  1. Hanein S, Dürr A, Ribai P, et al. A novel locus for autosomal dominant "uncomplicated" hereditary spastic paraplegia maps to chromosome 8p21.1-q13.3. Hum Genet 2007; 122:261-273. 

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