Hereditary spastic paraplegia type 36 (SPG36)

Written and reviewed by Dr Ibrahim Imam, Consultant Neurologist. Last reviewed .

Hereditary spastic paraplegia type 36 (SPG36). This is caused by mutations in chromosome 12q. Fully referenced neurology checklist.

Genetics

  • This is caused by mutations in chromosome 12q
  • The transmission is autosomal dominant
  • The mean onset age is 24 years

Clinical features

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Magnetic resonance imaging (MRI) brain

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References

  1. Schüle R, Bonin M, Dürr A, et al. Autosomal dominant spastic paraplegia with peripheral neuropathy maps to chr12q23-24. Neurology 2009; 72:1893-1898. 

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