Hereditary spastic paraplegia type 27 (SPG27)
Written and reviewed by Dr Ibrahim Imam, Consultant Neurologist. Last reviewed .
Hereditary spastic paraplegia type 27 (SPG27). This is caused by mutations in chromosome 10q. Fully referenced neurology checklist.
Genetics
- This is caused by mutations in chromosome 10q
- The transmission is autosomal recessive
- It is an early onset HSP
Clinical features
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Investigations
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References
- Ribai P, Stevanin G, Bouslam N, et al. A new phenotype linked to SPG27 and refinement of the critical region on chromosome. J Neurol 2006; 253:714-719.
- Meijer IA, Cossette P, Roussel J, Benard M, Toupin S, Rouleau GA. A novel locus for pure recessive hereditary spastic paraplegia maps to 10q22.1-10q24.1. Ann Neurol 2004; 56:579-582.
Related checklists
- Hereditary spastic paraplegia type 26 (SPG26)
- Hereditary spastic paraplegia type 28 (SPG28)
- Hereditary spastic paraplegia type 29 (SPG29)
- Hereditary spastic paraplegia type 30 (SPG30)
- Hereditary spastic paraplegia type 31 (SPG31)
- Hereditary spastic paraplegia type 32 (SPG32)
- Hereditary spastic paraplegia type 33 (SPG33)
- Hereditary spastic paraplegia type 34 (SPG34)
- Hereditary spastic paraplegia type 35 (SPG35)
- Hereditary spastic paraplegia type 36 (SPG36)
- Hereditary spastic paraplegia type 37 (SPG37)
- Hereditary spastic paraplegia type 38 (SPG38)
- Hereditary spastic paraplegia type 39 (SPG39)
- Hereditary spastic paraplegia type 40 (SPG40)
- Hereditary spastic paraplegia type 41 (SPG41)
- Hereditary spastic paraplegia type 42 (SPG42)
- Hereditary spastic paraplegia type 43 (SPG43)
- Hereditary spastic paraplegia type 44 (SPG44)
- Hereditary spastic paraplegia type 45 (SPG45)
- Hereditary spastic paraplegia type 46 (SPG46)
- Hereditary spastic paraplegia type 47 (SPG47)
- Hereditary spastic paraplegia type 48 (SPG48)
- Hereditary spastic paraplegia type 49 (SPG49)
- Hereditary spastic paraplegia type 50 (SPG50)
