First bite syndrome
Written and reviewed by Dr Ibrahim Imam, Consultant Neurologist. Last reviewed .
First bite syndrome. This is parotid region pain provoked by the first bite of each meal. Fully referenced neurology checklist.
Pathology
- This is parotid region pain provoked by the first bite of each meal
- It may occur with smelling the food or thinking of eating
- It results from parasympathetic hyperactivation
- It is associated with parotid region lesions or surgery
Clinical features
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Associated features
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Iatrogenic surgical causes
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Malignant causes
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Differential diagnosis
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Treatment
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References
- Costales-Marcos M, López Álvarez F, Fernández-Vañes L, Gómez J, Llorente JL. Treatment of the first bite syndrome. Acta Otorrinolaringol Esp 2017; 68:284-288.
- Steel SJ, Robertson CE. First bite syndrome: what neurologists need to know. Curr Pain Headache Rep 2021; 25:31.
- Tao MJ, Roche-Nagle G. First bite syndrome: a complication of carotid endarterectomy. BMJ Case Rep 2016; pii: bcr2015213996.
- Linkov G, Morris LG, Shah JP, Kraus DH. First bite syndrome: incidence, risk factors, treatment, and outcomes. Laryngoscope 2012; 122:1773-1778.
- Wang TK, Bhamidipaty V, MacCormick M. First bite syndrome following ipsilateral carotid endarterectomy. Vasc Endovascular Surg 2013; 47:148-150.
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