Edaravone
Written and reviewed by Dr Ibrahim Imam, Consultant Neurologist. Last reviewed .
Edaravone. Edaravone has antioxidant properties. It mainly improves pinch strength. Fully referenced neurology checklist.
Pharmacology and benefits
- Edaravone has antioxidant properties
- It mainly improves pinch strength
- It may delay progression of motor neurone disease (MND)
Dosing
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Side effects
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References
- Cruz MP. Edaravone (Radicava): a novel neuroprotective agent for the treatment of amyotrophic lateral sclerosis. P T. 2018; 43:25-28.
- Sawada H. Clinical efficacy of edaravone for the treatment of amyotrophic lateral sclerosis. Expert Opin Pharmacother 2017; 18:735-738.
- Writing Group; Edaravone (MCI-186) ALS 19 Study Group. Safety and efficacy of edaravone in well defined patients with amyotrophic lateral sclerosis: a randomised, double-blind, placebo-controlled trial. Lancet Neurol 2017; 16:505-512.
- Abe K, Itoyama Y, Sobue G, et al; Edaravone ALS Study Group. Confirmatory double-blind, parallel-group, placebo-controlled study of efficacy and safety of edaravone (MCI-186) in amyotrophic lateral sclerosis patients. Amyotroph Lateral Scler Frontotemporal Degener 2014; 15:610-617.
