Cervical internal carotid artery vasospasm (CICAV)

Written and reviewed by Dr Ibrahim Imam, Consultant Neurologist. Last reviewed .

Cervical internal carotid artery vasospasm (CICAV). This is recurrent cervical internal carotid artery vasospasm syndrome (RCICAV).

Causes: idiopathic

  • This is recurrent cervical internal carotid artery vasospasm syndrome (RCICAV)
  • It is bilateral in about 70% of cases
  • It is recurrent in about 15% of cases
  • It has been linked to ACOX3 and PTGIS gene mutations

Causes: others

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Clinical features

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Differential diagnosis

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Investigations

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Treatments

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Attempted treatments

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Synonym

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References

  1. Janzarik WG, Ringleb PA, Reinhard M, Rauer S. Recurrent extracranial carotid artery vasospasms: report of 2 cases. Stroke 2006; 37:2170-2173.
  2. Dembo T, Tanahashi N. Recurring extracranial internal carotid artery vasospasm detected by intravascular ultrasound. Intern Med 2012; 51:1249-1253.
  3. Graham E, Orjuela K, Poisson S, Biller J. Treatment challenges in idiopathic extracranial ICA vasospasm case report and review of the literature. eNeurologicalSci 2020; 22:100304. 
  4. Shimoda Y, Fujimura M, Kimura N, Ezura M, Uenohara H, Tominaga T. Recurrent extracranial internal carotid artery vasospasm diagnosed by serial magnetic resonance angiography and superselective transarterial injection of a calcium channel blocker. J Stroke Cerebrovasc Dis 2014; 23:e383-e387.
  5. Fang J, Jiang N, Zhou Y, Shen H, Han F, Ni J. Idiopathic extracranial internal carotid artery vasospasm: case report and systematic review. Neurol Sci 2024; 45:5639-5655.
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