Anti U1-RNP myopathy
Written and reviewed by Dr Ibrahim Imam, Consultant Neurologist. Last reviewed .
Anti U1-RNP myopathy. Mixed connective tissue disease (MCTD), Systemic lupus erythematosus (SLE). Fully referenced neurology checklist.
Clinical phenotypes
- Mixed connective tissue disease (MCTD)
- Systemic lupus erythematosus (SLE)
Clinical features
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Differential diagnosis
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Investigations
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References
- Casal-Dominguez M, Pinal-Fernandez I, Corse AM, et al. Muscular and extramuscular features of myositis patients with anti-U1-RNP autoantibodies. Neurology 2019; 92:e1416-e1426.
- Ge Y, Yang H, Jiang W, Tian X, Lu X, Wang G. Clinical characteristics of myositis patients with isolated anti-U1 ribonucleoprotein antibody resemble immune-mediated necrotizing myopathy. Ther Adv Musculoskelet Dis 2023; 15:1759720X231181336.
- Dima A, Jurcut C, Baicus C. The impact of anti-U1-RNP positivity: systemic lupus erythematosus versus mixed connective tissue disease. Rheumatol Int 2018; 38:1169-1178.
