Viliuisk encephalomyelitis
Written and reviewed by Dr Ibrahim Imam, Consultant Neurologist. Last reviewed .
Viliuisk encephalomyelitis. This is an acute meningoencephalitis that progresses to a chronic panencephalitis. Fully referenced neurology checklist.
Epidemiology
- This is an acute meningoencephalitis that progresses to a chronic panencephalitis
- It is probably infectious but the cause has not been identified
- It is endemic along the Viliui River and Yakutsk town in Eastern Siberia
- It predominantly affects young adults
- It is transmitted by close household contact
- The outcome is worse in secondary cases
Pathology
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Potential infectious candidates
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Acute features
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Chronic features
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Cerebrospinal fluid (CSF) analysis
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Brain imaging
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References
- Vladimirtsev VA, Nikitina RS, Renwick N, et al. Family clustering of Viliuisk encephalomyelitis in traditional and new geographic regions. Emerg Infect Dis 2007; 13:1321-1326.
- Lee HS, Zhdanova SN, Vladimirtsev VA, et al. Epidemiology of Viliuisk encephalomyelitis in Eastern Siberia. Epidemiology 2010; 21:24-30.
- Storch A, Kassubek J, Tumani H, et al. Communicating hydrocephalus following eosinophilic meningitis is pathogenic for chronic Viliuisk encephalomyelitis in Northeastern Siberia. PLoS One 2014; 9:e84670.
- Goldfarb LG, Vladimirtsev VA, Platanov FA, Lee HS, McLean CA, Masters CL. Viliuisk encephalomyelitis in Eastern Siberia - analysis of 390 cases. Folia Neuropathol 2009; 47:171-181.
- Chumakov KM, Karavanov AS. Preliminary characterization of an organism isolated from a case of Viluy encephalomyelitis indicates a protozoal, rather than viral, aetiology. J Gen Microbiol 1986; 132:1127-1133.
