Powassan virus (POWV) encephalitis

Written and reviewed by Dr Ibrahim Imam, Consultant Neurologist. Last reviewed .

Powassan virus (POWV) encephalitis. This is a tick-borne flavivirus. Fully referenced neurology checklist.

Virology

  • This is a tick-borne flavivirus
  • It is transmitted by the deer tick Ixodes scapularis

Hosts

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Clinical features

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Differential diagnosis

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Cerebrospinal fluid (CSF) analysis

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Magnetic resonance imaging (MRI) brain: features

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Viral identification

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Precautions against tick bites

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Management

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References

  1. Sung S, Wurcel AG, Whittier S, et al. Powassan meningoencephalitis, New York, New York, USA. Emerg Infect Dis 2013; 19. 
  2. Piantadosi A, Rubin DB, McQuillen DP, et al. Emerging cases of powassan virus encephalitis in New England: clinical presentation, imaging, and review of the literature. Clin Infect Dis 2016; 62:707-713.
  3. El Khoury MY, Camargo JF, White JL, et al. Potential role of deer tick virus in Powassan encephalitis cases in Lyme disease-endemic areas of New York, U.S.A. Emerg Infect Dis 2013; 19:1926-1933. 
  4. Raval M, Singhal M, Guerrero D, Alonto A. Powassan virus infection: case series and literature review from a single institution. BMC Res Notes 2012; 5:594.
  5. Hicar MD, Edwards K, Bloch K. Powassan virus infection presenting as acute disseminated encephalomyelitis in Tennessee. Pediatr Infect Dis J 2011; 30:86-88. 
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