Tick borne encephalitis virus (TBEV)
Written and reviewed by Dr Ibrahim Imam, Consultant Neurologist. Last reviewed .
Tick borne encephalitis virus (TBEV). This is a flavivirus. Fully referenced neurology checklist.
Biology
- This is a flavivirus
- The transmission is by Ixodes ricinus, persulcatus and ovatus ticks
- It is transmitted through unpasteurized cow, goat, or sheep dairy products
- It is maintained in rodents
- The infection is highest between April and November
Biphasic presentation
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Clinical phenotypes
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Clinical features
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Cerebrospinal fluid (CSF) analysis
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Blood investigations
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Indications for vaccination
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Treatment
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Poor prognostic factors
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References
- Taba P, Schmutzhard E, Forsberg P, et al. EAN consensus review on prevention, diagnosis and management of tick-borne encephalitis. Eur J Neurol 2017; 24:1214-e61.
- Bogovic P, Strle F. Tick-borne encephalitis: a review of epidemiology, clinical characteristics, and management. World J Clin Cases 2015; 3:430-441.
- Zavadska D, Anca I, André F, et al. Recommendations for tick-borne encephalitis vaccination from the Central European Vaccination Awareness Group (CEVAG). Hum Vaccin Immunother 2013; 9:362-374.
- Logina I, Krumina A, Karelis G, et al. Clinical features of double infection with tick-borne encephalitis and Lyme borreliosis transmitted by tick bite. JNNP 2006; 77:1350-1353.
- Skudal H, Lorentzen ÅR, Stenstad T, et al. Long-term patient-reported neurocognitive and functional outcomes after tick-borne encephalitis: a prospective controlled multicenter cohort study. J Neurol 2026; 273:554.
