Upbeat nystagmus

Written and reviewed by Dr Ibrahim Imam, Consultant Neurologist. Last reviewed .

Upbeat nystagmus. This is usually caused by damage to the brainstem vestibulo-ocular pathways. Fully referenced neurology checklist.

Pathogenesis

  • This is usually caused by damage to the brainstem vestibulo-ocular pathways
  • The lesions are usually in the middle or superior cerebellar peduncles

Causes

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Clinical features

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Associated features

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Treatment

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References

  1. Kim JS, Yoon B, Choi KD, Oh SY, Park SH, Kim BK. Upbeat nystagmus: clinicoanatomical correlations in 15 patients. J Clin Neurol 2006; 2:58-65.
  2. Serra A, Leigh RJ. Diagnostic value of nystagmus: spontaneous and induced ocular oscillations. JNNP 2002; 73:615–618.
  3. Munro NA, Gaymard B, Rivaud S, Majdalani A, Pierrot-Deseilligny C. Upbeat nystagmus in a patient with a small medullary infarct. JNNP 1993; 56:1126-1128.
  4. Lee SC, Lee SH, Lee KY, Lee YJ, Koh SH. Transient upbeat nystagmus due to unilateral focal pontine infarction. J Clin Neurosci 2009; 16:563-565.
  5. Hirose G, Ogasawara T, Shirakawa T, et al. Primary position upbeat nystagmus due to unilateral medial medullary infarction. Ann Neurol 1998; 43:403-406.
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