Nystagmus: physiology and causes

Written and reviewed by Dr Ibrahim Imam, Consultant Neurologist. Last reviewed .

Nystagmus: physiology and causes. Nystagmus describes repetitive involuntary eye movements. Fully referenced neurology checklist.

Definition

  • Nystagmus describes repetitive involuntary eye movements
  • They start with slow drifts of the eye away from the target
  • In pendular nystagmus, the to and fro movements are sinusoidal
  • In jerk nystagmus the corrective saccadic movement is fast

Mechanisms that prevent nystagmus

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Physiological causes

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Visual pathway causes

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Neurological causes

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Drug-induced causes

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Differential diagnosis

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References

  1. Serra A, Leigh RJ. Diagnostic value of nystagmus: spontaneous and induced ocular oscillations. JNNP 2002; 73:615–618.
  2. Abadi RV. Mechanisms underlying nystagmus. J R Soc Med 2002; 95:231–234.
  3. Stahl JS, Plant GT, Leigh RJ. Medical treatment of nystagmus and its visual consequences. J R Soc Med 2002; 95:235-237.
  4. Balani A, Kumar AD, Marda SS, Alwala S. Nondecussating retinal-fugal fiber syndrome: Clinical and neuroimaging clues to diagnosis. Indian J Ophthalmol 2015; 63:858-861. 

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