Ublituximab
Written and reviewed by Dr Ibrahim Imam, Consultant Neurologist. Last reviewed .
Ublituximab. Ublituximab is a glycoengineered anti-CD20 monoclonal antibody. Fully referenced neurology checklist.
Pharmacology
- Ublituximab is a glycoengineered anti-CD20 monoclonal antibody
- It depletes B cells by antibody-dependent cellular cytotoxicity
Pharmacology
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Dosing
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Precautions
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Adverse events
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References
- Lee A. Ublituximab: first approval. Drugs 2023; 83:455-459.
- Fox E, Lovett-Racke AE, Gormley M, et al. A phase 2 multicenter study of ublituximab, a novel glycoengineered anti-CD20 monoclonal antibody, in patients with relapsing forms of multiple sclerosis. Mult Scler. 2021; 27:420-429.
- Mukhtar H, Yasmeen U, Siddiqa S, Sarfraz Z, Sarfraz A. Outcomes of Ublituximab compared to Teriflunomide for relapsing multiple sclerosis: a meta-analysis. Mult Scler Relat Disord 2022; 65:104002.
