Transient global amnesia (TGA): clinical features
Written and reviewed by Dr Ibrahim Imam, Consultant Neurologist. Last reviewed .
Transient global amnesia (TGA): clinical features. TGA is characterised by an episode of abrupt onset amnesia. Fully referenced neurology checklist.
Onset and duration
- TGA is characterised by an episode of abrupt onset amnesia
- The duration is usually 1-24 hours but 3% of cases last <1 hour
- The onset is usually in the morning but not on awakening
- It is recurrent in 6-30% of cases
- Recurrence can occur multiple times
Amnesia features
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Associated neurological features
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Associated cardiac features
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Other associated features
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Exclusion criteria
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Diagnostic criteria
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Possible predictors of recurrent TGA
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References
- Kirshner HS. Transient global amnesia: a brief review and update. Curr Neurol Neurosci Rep 2011; 11:578-582.
- Quinette P, Guillery-Girard B, Dayan J, et al. What does transient global amnesia really mean? Review of the literature and thorough study of 142 cases. Brain 2006; 129:1640-1658.
- Brigo F, Tezzon F, Nardone R. "Once again she forgets everything!": a patient with four episodes of transient global amnesia within less than 5 years. Acta Neurol Belg 2018; 118:319-320.
- Piffer S, Nannoni S, Maulucci F, et al. Transient global amnesia with unexpected clinical and radiological findings: A case series and systematic review. J Neurol Sci 2022; 441:120349.
- Nagamine T. Transient global amnesia with transient anosmia: a curious case suggestive of middle cerebral artery occlusion. J Integr Neurosci 2022; 21:103.
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