Stiff person syndrome (SPS): investigational treatments
Written and reviewed by Dr Ibrahim Imam, Consultant Neurologist. Last reviewed .
Stiff person syndrome (SPS): investigational treatments. Ocrelizumab, Ofatumumab, Inebilizumab, Ublituximab. Fully referenced neurology checklist.
Anti B cell agents
- Ocrelizumab
- Ofatumumab
- Inebilizumab
- Ublituximab
- Obexelimab
- Obinutuzumab
- Obinutuzumab
- Bortezomib
- Daratumumab
FcRn inhibitors
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Bruton kinase inhibitors
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Anti IL6 receptor antagonists
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References
- Dalakas MC. Therapies in stiff-person syndrome: advances and future prospects based on disease pathophysiology. Neurol Neuroimmunol Neuroinflamm 2023; 10:e200109.
- Di Stefano V, Alonge P, Rini N, Militello M, Lupica A, Torrente A, Brighina F. Efgartigimod beyond myasthenia gravis: the role of FcRn-targeting therapies in stiff-person syndrome. J Neurol 2024; 271:254-262.
