Sleeping sickness: pathology
Written and reviewed by Dr Ibrahim Imam, Consultant Neurologist. Last reviewed .
Sleeping sickness: pathology. This is the West African form. It is transmitted by the tsetse fly Glossina palpalis. Fully referenced neurology checklist.
Trypanosoma brucei gambiense
- This is the West African form
- It is transmitted by the tsetse fly Glossina palpalis
- Humans are the main reservoirs
- It accounts for 97% of human infections
- It causes chronic infection lasting about three years
Trypanosoma brucei rhodesiense
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Transmission
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Routes of entry into the central nervous system
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Pathology
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Synonyms
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References
- Dzikowiec M, Góralska K, Błaszkowska J. Neuroinvasions caused by parasites. Ann Parasitol 2017; 63:243–253.
- Malvy D, Chappuis F. Sleeping sickness. Clin Microbiol Infect 2011; 17:986-995.
- Ehrhardt S, Lippert U, Burchard GD, Sudeck H. Orchitis as an unusual manifestation of human African trypanosomiasis. J Infect 2006; 52:e31-e33.
- Kennedy PG. Human African trypanosomiasis of the CNS: current issues and challenges. J Clin Invest 2004; 113:496-504.
