Sepsis associated encephalopathy (SAE): clinical features
Written and reviewed by Dr Ibrahim Imam, Consultant Neurologist. Last reviewed .
Sepsis associated encephalopathy (SAE): clinical features. Subsyndromal delirium, Sepsis associated delirium (SAD). Fully referenced neurology checklist.
Neurological features
- Subsyndromal delirium
- Sepsis associated delirium (SAD)
- Inattention
- Disorientation
- Coma
- Altered sleep–wake cycle
- Seizures
- Posterior reversible encephalopathy syndrome (PRES)
- Critical illness myoneuropathy
Movement disorders
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Psychiatric features
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Systemic features
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Screening tools
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Outcomes: long-term cognitive impairment
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Outcomes: psychiatric
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Synonym
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References
- Gofton TE, Young GB. Sepsis-associated encephalopathy. Nat Rev Neurol 2012; 8:557-566.
- Sonneville R, de Montmollin E, Poujade J, et al. Potentially modifiable factors contributing to sepsis-associated encephalopathy. Intensive Care Med 2017; 43:1075-1084.
- Mazeraud A, Righy C, Bouchereau E, Benghanem S, Bozza FA, Sharshar T. Septic-associated encephalopathy: a comprehensive review. Neurotherapeutics 2020; 17:392-403.
- Golzari SE, Mahmoodpoor A. Sepsis-associated encephalopathy versus sepsis-induced encephalopathy. Lancet Neurol 2014; 13:967-968.
- Atterton B, Paulino MC, Povoa P, Martin-Loeches I. Sepsis associated delirium. Medicina (Kaunas) 2020; 56:240.
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