Schizophrenia: treatment
Written and reviewed by Dr Ibrahim Imam, Consultant Neurologist. Last reviewed .
Schizophrenia: treatment. Clozapine: this is the most effective, Olanzapine, Risperidone, Quetiapine, Paliperidone. Fully referenced neurology checklist.
Second generation antipsychotics
- Clozapine: this is the most effective
- Olanzapine
- Risperidone
- Quetiapine
- Paliperidone
- Ziprasidone
- Molindone
Third generation antipsychotics
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First generation antipsychotics: rarely used
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Non-drug treatments
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References
- Picchioni MM, Murray RM. Schizophrenia. BMJ 2007; 335:91-95.
- Stępnicki P, Kondej M, Kaczor AA. Current concepts and treatments of schizophrenia. Molecules 2018; 23:2087.
- Faden J, Citrome L. Resistance is not futile: treatment-refractory schizophrenia - overview, evaluation and treatment. Expert Opin Pharmacother 2019; 20:11-24.
- Xu F, Xu S. Cognitive-behavioral therapy for negative symptoms of schizophrenia: A systematic review and meta-analysis. Medicine (Baltimore) 2024; 103:e39572.