REM sleep behaviour disorder (RBD): risk factors

Written and reviewed by Dr Ibrahim Imam, Consultant Neurologist. Last reviewed .

REM sleep behaviour disorder (RBD): risk factors. Parkinson’s disease (PD), Lewy body disease (LBD). Fully referenced neurology checklist.

Synucleinopathies

  • Parkinson’s disease (PD)
  • Lewy body disease (LBD)
  • Multiple system atrophy (MSA)
  • Primary autonomic failure (PAF)

Tauopathies

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Other neurodegenerative diseases

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Drug-induced

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Other causes

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Potential risk factors

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References

  1. Thomas A, Bonanni L, Onofrj M. Symptomatic REM sleep behaviour disorder. Neurol Sci 2007; 28:S21-S36.
  2. Boeve BF, Silver MH, Saper CB, et al. Pathophysiology of REM sleep behaviour disorder and relevance to neurodegenerative disease. Brain 2007; 130:2770-2788.
  3. Iranzo A, Santamaria J, Tolosa E. Idiopathic rapid eye movement sleep behaviour disorder: diagnosis, management, and the need for neuroprotective interventions. Lancet Neurol 2016; 15:405-419. 
  4. Iranzo A, Stefani A, Serradell M, et al; SINBAR (Sleep Innsbruck Barcelona) group. Characterization of patients with longstanding idiopathic REM sleep behavior disorder. Neurology 2017; 89:242-248. 
  5. Postuma RB, Montplaisir JY, Pelletier A, et al. Environmental risk factors for REM sleep behavior disorder: a multicenter case-control study. Neurology 2012; 79:428-434.
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