REM sleep behaviour disorder (RBD): differential diagnosis

Written and reviewed by Dr Ibrahim Imam, Consultant Neurologist. Last reviewed .

REM sleep behaviour disorder (RBD): differential diagnosis. Narcolepsy, Periodic limb movements in sleep (PLMS). Fully referenced neurology checklist.

Sleep related differentials

  • Narcolepsy
  • Periodic limb movements in sleep (PLMS)
  • Nocturnal frontal lobe epilepsy
  • Sleepwalking
  • Sleep terror
  • Epilepsy
  • Post-traumatic stress disorder (PTSD)
  • Confusional arousal
  • Alcohol/drugs and withdrawal

Obstructive sleep apnoea (OSA)

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Psychiatric disorders

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References

  1. Fantini ML, Puligheddu M, Cicolin A. Sleep and violence. Curr Treat Options Neurol 2012; 24:438-450.
  2. Boeve BF. REM sleep behaviour disorder: updated review of the core features, the RBD-neurodegenerative disease association, evolving concepts, controversies, and future directions. Ann N Y Acad Sci 2010; 1184:15-54.
  3. Stores G. Clinical diagnosis and misdiagnosis of sleep disorders. JNNP 2007; 78:1293-1297.
  4. Iranzo A, Santamaria J, Tolosa E. Idiopathic rapid eye movement sleep behaviour disorder: diagnosis, management, and the need for neuroprotective interventions. Lancet Neurol 2016; 15:405-419.

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