Post thymectomy thymoma recurrence

Written and reviewed by Dr Ibrahim Imam, Consultant Neurologist. Last reviewed .

Post thymectomy thymoma recurrence. Thymomas recur post thymectomy in 15% of invasive cases. Fully referenced neurology checklist.

Epidemiology

  • Thymomas recur post thymectomy in 15% of invasive cases
  • The recurrence develops 2 to 16 years after thymectomy
  • Multiple recurrences occur in some cases
  • Recurrence with metastases may also occur

General predictors of recurrence

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Infective predictors

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Dermatological predictors

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Non-predictors

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References

  1. Evoli A, Minisci C, Di Schino C, et al. Thymoma in patients with MG: characteristics and long-term outcome. Neurology 2002; 59:1844-1850.
  2. Skeie GO, Apostolski S, Evoli A, et al. Guidelines for treatment of autoimmune neuromuscular transmission disorders. Eur J Neurol 2010; 17:893-902.
  3. Evoli A, Minisci C, Di Schino C, et al. Thymoma in patients with MG: characteristics and long-term outcome. Neurology 2002; 59:1844-1850.
  4. Gastaldi M, De Rosa A, Maestri M, et al. Acquired neuromyotonia in thymoma-associated myasthenia gravis: a clinical and serological study. Eur J Neurol 2019; 26:992-999. 
  5. De Rosa A, Fornili M, Maestri Tassoni M, et al. Thymoma-associated myasthenia gravis: clinical features and predictive value of antiacetylcholine receptor antibodies in the risk of recurrence of thymoma. Thorac Cancer 2021; 12:106-113.
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