Parkinson's disease (PD): systemic features

Written and reviewed by Dr Ibrahim Imam, Consultant Neurologist. Last reviewed .

Parkinson's disease (PD): systemic features. Seborrheic dermatitis, Sweating disorders: hyper or hypohidrosis. Fully referenced neurology checklist.

Non-iatrogenic dermatological features

  • Seborrheic dermatitis
  • Sweating disorders: hyper or hypohidrosis
  • Rosacea
  • Perioral dermatitis
  • Bullous pemphigoid
  • α synuclein deposition in the skin

Iatrogenic dermatological features

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Gastrointestinal features

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Rheumatological features

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Cancer risk

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Driving impairment

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Cardiovascular features

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Other systemic features

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References

  1. Niemann N, Billnitzer A, Jankovic J. Parkinson's disease and skin. Parkinsonism Relat Disord 2021; 82:61-76.
  2. Martignoni E, Godi L, Pacchetti C, et al. Is seborrhea a sign of autonomic impairment in Parkinson's disease? J Neural Transm (Vienna) 1997; 104:1295-1304.
  3. Gibbons CH, Garcia J, Wang N, Shih LC, Freeman R. The diagnostic discrimination of cutaneous α-synuclein deposition in Parkinson disease. Neurology 2016; 87:505-512.
  4. Komagamine T, Suzuki K, Hirata K. Darkening of white hair following levodopa therapy in a patient with Parkinson's disease. Mov Disord 2013; 28:1643.
  5. Rodrigues B, Nóbrega AC, Sampaio M, Argolo N, Melo A. Silent saliva aspiration in Parkinson's disease. Mov Disord 2011; 26:138-141. 
  6. And 22 more. Subscribe to see the full list

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