Parkinson's disease (PD): peripheral neuropathy

Written and reviewed by Dr Ibrahim Imam, Consultant Neurologist. Last reviewed .

Parkinson's disease (PD): peripheral neuropathy. Severity of PD, Levodopa exposure: levodopa-induced neuropathy. Fully referenced neurology checklist.

Risk factors

  • Severity of PD
  • Levodopa exposure: levodopa-induced neuropathy
  • Vitamin B12 deficiency
  • Hyperhomocysteinaemia
  • PD degeneration

Genetic disorders manifesting with PD and PN

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PD neuropathy types

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References

  1. Merola A, Rosso M, Romagnolo A, et al. Peripheral neuropathy as marker of severe Parkinson's disease phenotype. Mov Disord 2017; 32:1256-1258.
  2. Ceravolo R, Cossu G, Bandettini di Poggio M, et al. Neuropathy and levodopa in Parkinson's disease: evidence from a multicenter study. Mov Disord 2013; 28:1391-1397.
  3. Romagnolo A, Merola A, Artusi CA, Rizzone MG, Zibetti M, Lopiano L. Levodopa-induced neuropathy: a systematic review. Mov Disord Clin Pract 2018; 6:96-103.
  4. Rajabally YA, Martey J. Neuropathy in Parkinson disease: prevalence and determinants. Neurology 2011; 77:1947-1950.
  5. Zis P, Grünewald RA, Chaudhuri RK, Hadjivassiliou M. Peripheral neuropathy in idiopathic Parkinson's disease: A systematic review. J Neurol Sci 2017; 378:204-209.
  6. And 8 more. Subscribe to see the full list

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