Parkinson’s disease (PD): cognitive features

Written and reviewed by Dr Ibrahim Imam, Consultant Neurologist. Last reviewed .

Parkinson’s disease (PD): cognitive features. Mild cognitive impairment, Dementia. Fully referenced neurology checklist.

Clinical features

  • Mild cognitive impairment
  • Dementia
  • Cognition is reportedly worse when supine

Predictors

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Cognitive modifiers

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References

  1. Centi J, Freeman R, Gibbons CH, Neargarder S, Canova AO, Cronin-Golomb A. Effects of orthostatic hypotension on cognition in Parkinson disease. Neurology 2017; 88:17-24. 
  2. Chaudhuri KR, Schapira AH. Non-motor symptoms of Parkinson’s disease: dopaminergic pathophysiology and treatment. Lancet Neurol 2009; 8:464-474.
  3. Suzuki A, Hoshino T, Shigemasu K, Kawamura M. Disgust-specific impairment of facial expression recognition in Parkinson's disease. Brain 2006; 129:707-717.
  4. Martinez-Nunez AE, Mills KA, Seemiller J, Morrow CB, Pontone GM, Mahajan A. Early autonomic burden in prodromal Parkinson's disease predicts cognitive impairment. Mov Disord 2026; 41:1299-1303.
  5. Goldman JG, Bledsoe IO, Merkitch D, Dinh V, Bernard B, Stebbins GT. Corpus callosal atrophy and associations with cognitive impairment in Parkinson disease. Neurology 2017; 88:1265-1272.
  6. And 6 more. Subscribe to see the full list

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