Opioid-associated amnestic syndrome (OAS)
Written and reviewed by Dr Ibrahim Imam, Consultant Neurologist. Last reviewed .
Opioid-associated amnestic syndrome (OAS). It is most frequently caused by Fentanyl. Fully referenced neurology checklist.
Pathology
- It is most frequently caused by Fentanyl
- It has also been reported with Hydromorphone
Demographic features
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Diagnostic criteria
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Magnetic resonance imaging (MRI) brain
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Magnetic resonance spectroscopy (MRS) brain
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Other investigations
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Clinical differentials
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Radiological differentials
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References
- Ciurylo W, Noh E. Opioid-associated amnestic syndrome. Cureus 2021; 13:e16714.
- Walker ML, Patel K, Li T, Kassir M. Opioid-associated amnestic syndrome. Cureus 2021; 13:e20056.
- Taylor RG, Budhram A, Lee DH, Mirsattari SM. Opioid-associated amnestic syndrome observed with fentanyl patch use. CMAJ 2019; 191:E337-E339.
- Barash JA, Kofke WA. Connecting the dots: an association between opioids and acute hippocampal injury. Neurocase 2018; 24:124-131.
- Barash JA, Whitledge J, Watson CJ, et al. Opioid-associated amnestic syndrome: description of the syndrome and validation of a proposed definition. J Neurol Sci 2020; 417:117048.
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