CHANTER syndrome
Written and reviewed by Dr Ibrahim Imam, Consultant Neurologist. Last reviewed .
CHANTER syndrome. Fentanyl, Hydromorphone, Heroin. Fully referenced neurology checklist.
Provoking agents
- Fentanyl
- Hydromorphone
- Heroin
Pathogenetic mechanisms
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Clinical features
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Paediatric opioid-use-associated neurotoxicity with cerebellar edema (POUNCE
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Differential diagnosis
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Magnetic resonance imaging (MRI)
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Pathological features
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Other investigations
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Treatment
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Possible outcomes
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Acronym
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References
- Jasne AS, Alsherbini KH, Smith MS, Pandhi A, Vagal A, Kanter D. Cerebellar hippocampal and basal nuclei transient edema with restricted diffusion (CHANTER) syndrome. Neurocrit Care 2019; 31:288-296.
- Mallikarjun KS, Parsons MS, Nigogosyan Z, Goyal MS, Eldaya RW. Neuroimaging findings in CHANTER syndrome: a case series. AJNR 2022; 43:1136-1141.
- Atac MF, Vilanilam GK, Damalcheruvu PR, Pandey I, Vattoth S. Cerebellar, hippocampal, and basal nuclei transient edema with restricted diffusion (CHANTER) syndrome in the setting of opioid and phencyclidine use. Radiol Case Rep 2023; 18:3496-3500.
- Zhou YMJ, Shah M, Fayngersh A. A case of cerebellar hippocampal and basal nuclei transient edema with restricted diffusion syndrome with poor clinical outcome. Cureus 2022; 14:e22767.
- Sotiropoulos MG, Harrison DS, Zusman BE, Puccetti MV, Molyneaux BJ. CHANTER syndrome: an under-recognized cause of reversible hydrocephalus after opioid overdose. Neurol Sci 2024 (Online ahead of print).
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