Myoclonus: treatment

Written and reviewed by Dr Ibrahim Imam, Consultant Neurologist. Last reviewed .

Myoclonus: treatment. Clonazepam, Levetiracetam, Piracetam, Perampanel: this is promising. Fully referenced neurology checklist.

Generic myoclonus treatments

  • Clonazepam
  • Levetiracetam
  • Piracetam
  • Perampanel: this is promising

Treatment of cortical myoclonus

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Treatment of subcortical myoclonus

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Treatment of spinal myoclonus

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Treatment of palatal myoclonus

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Treatment of epileptic myoclonus

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Treatments of opsoclonus-myoclonus syndrome (OMS)

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Other treatments

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Treatments to avoid

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References

  1. Dijk JM, Tijssen MAJ. Management of patients with myoclonus: available therapies and the need for an evidence-based approach. Lancet Neurol 2010; 9:1028-1036.
  2. Kojovic M, Cordivari C, Bhatia K. Myoclonic disorders: a practical approach for diagnosis and treatment. Ther Adv Neurol Disord 2011; 4:47-62.
  3. Mir A, Alghamdi A, Alotaibi W, Samreen D, Alotaibi M, Albaradie R, Bashir S. A systematic review of the efficacy of perampanel as treatment for myoclonic seizures and symptomatic myoclonus. Epileptic Disord 2022; 24:633-646.

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