Motor neurone disease (MND): other features

Written and reviewed by Dr Ibrahim Imam, Consultant Neurologist. Last reviewed .

Motor neurone disease (MND): other features. Insomnia, Fragmented sleep, Periodic limb movements of sleep (PLMS). Fully referenced neurology checklist.

Sleep disorders

  • Insomnia
  • Fragmented sleep
  • Periodic limb movements of sleep (PLMS)

Cognitive impairments

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Neuropsychiatric features

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Autonomic dysfunction

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Pain

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Movement disorders

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Risk of cancer

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Other features

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Behavioural assessment tools

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References

  1. Mitsumoto H. Diagnosis and progression of ALS. Neurology 1997; 48(Suppl 4):S2- S8.
  2. Lo Coco D, Puligheddu M, Mattaliano P, et al. REM sleep behavior disorder and periodic leg movements during sleep in ALS. Acta Neurol Scand 2016; doi: 10.1111/ane.12593 (Epub ahead of print).
  3. Beeldman E, Raaphorst J, Klein Twennaar M, de Visser M, Schmand BA, de Haan RJ. The cognitive profile of ALS: a systematic review and meta-analysis update. JNNP 2016; 87:611-619.
  4. Roos E, Mariosa D, Ingre C, et al. Depression in amyotrophic lateral sclerosis. Neurology 2016; 86:2271-2277.
  5. Turner MR, Goldacre R, Talbot K, Goldacre MJ. Psychiatric disorders prior to amyotrophic lateral sclerosis. Ann Neurol 2016; 80:935-938.
  6. And 16 more. Subscribe to see the full list

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