Motor neurone disease (MND): diagnostic criteria
Written and reviewed by Dr Ibrahim Imam, Consultant Neurologist. Last reviewed .
Motor neurone disease (MND): diagnostic criteria. Awaji, Revised El Escorial, Gold Coast. Fully referenced neurology checklist.
Diagnostic classification systems
- Awaji
- Revised El Escorial
- Gold Coast
Neurophysiological requirements
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Clinical requirements
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Definite ALS
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Probable ALS
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Probable ALS-laboratory supported
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Possible ALS
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References
- Costa J, Swash M, de Carvalho M. Awaji criteria for the diagnosis of amyotrophic lateral sclerosis: a systematic review. Arch Neurol 2012; 69:1410-1416.
- Geevasinga N, Menon P, Scherman DB, et al. Diagnostic criteria in amyotrophic lateral sclerosis: a multicenter prospective study. Neurology 2016; 87:684-690.
- Brooks BR. El Escorial World Federation of Neurology criteria for the diagnosis of amyotrophic lateral sclerosis. Subcommittee on Motor Neuron Diseases/Amyotrophic Lateral Sclerosis of the World Federation of Neurology Research Group on Neuromuscular Diseases and the El Escorial "Clinical limits of amyotrophic lateral sclerosis" workshop contributors. J Neurol Sci 1994; 124(Suppl):96-107.
- de Carvalho M, Dengler R, Eisen A, et al. Electrodiagnostic criteria for diagnosis of ALS. Clin Neurophysiol 2008; 119:497-503.
- Brooks BR, Miller RG, Swash M, Munsat TL. World Federation of Neurology Research Group on Motor Neuron Diseases. El Escorial revisited: revised criteria for the diagnosis of amyotrophic lateral sclerosis. Amyotroph Lateral Scler Other Motor Neuron Disord 2000; 1:293-299.
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