MELAS stroke-like episodes (SLEs): clinical features
Written and reviewed by Dr Ibrahim Imam, Consultant Neurologist. Last reviewed .
MELAS stroke-like episodes (SLEs): clinical features. These are metabolic strokes. Fully referenced neurology checklist.
Pathology
- These are metabolic strokes
- They arise from focal breakdown of the blood-brain barrier
Epidemiology
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Triggers
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Clinical features
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Differential diagnosis: other causes of SLEs
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Acronym
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References
- Finsterer J, Aliyev R. Metabolic stroke or stroke-like lesion: peculiarities of a phenomenon. J Neurol Sci 2020; 412:116726.
- Finsterer J. Mitochondrial metabolic stroke: phenotype and genetics of stroke-like episodes. J Neurol Sci 2019; 400:135-141.
- Finsterer J. Therapeutic management of stroke-like episodes varies from that of encephalitis. Medicine (Baltimore) 2020; 99:e19141.
- Martinez-Fernandez E, Gil-Peralta A, Garcia-Lozano R, et al. Mitochondrial disease and stroke. Stroke 2001; 32:2507-2510.
- Durrleman C, Grevent D, Aubart M, et al. Clinical and radiological description of 120 pediatric stroke-like episodes. Eur J Neurol 2023; 30:2051-2061.
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