MELAS: MRI features
Written and reviewed by Dr Ibrahim Imam, Consultant Neurologist. Last reviewed .
MELAS: MRI features. See Neurochecklist: “MELAS: Stroke-like episodes”. Fully referenced neurology checklist.
Stroke-like episodes
- See Neurochecklist: “MELAS: Stroke-like episodes”
Basal ganglia calcifications
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Progressive brain infarcts
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Apparent diffusion coefficient (ADC) features
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Diffusion weighted MR spectroscopy
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Other MRI features of MELAS
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Acronym
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References
- Sue CM, Crimmins DS, Soo YS, et al. Neuroradiological features of six kindreds with MELAS tRNA(Leu) A2343G point mutation: implications for pathogenesis. JNNP 1998; 65:233-240.
- Oppenheim C, Galanaud D, Samson Y, Sahel M, Dormont D, Wechsler B, Marsault C. Can diffusion weighted magnetic resonance imaging help differentiate stroke from stroke-like events in MELAS? JNNP 2000; 69:248-250.
- Liu Z, Zheng D, Wang X, Zhang J, Xie S, Xiao J, Jiang X. Apparent diffusion coefficients of metabolites in patients with MELAS using diffusion-weighted MR spectroscopy. Am J Neuroradiol 2011; 32:898-902.
- Whitehead MT, Wien M, Lee B, Bass N, Gropman A. Cortical venous disease severity in MELAS syndrome correlates with brain lesion development. Neuroradiology 2017; 59:813-818.
- Finsterer J. Characteristics of stroke-like lesions on cerebral imaging. Ideggyogy Sz 2023; 76:5-10.
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