MELAS: management
Written and reviewed by Dr Ibrahim Imam, Consultant Neurologist. Last reviewed .
MELAS: management. Lactic acid, Pyruvic acid, Mitochondrial DNA analysis. Fully referenced neurology checklist.
Blood tests
- Lactic acid
- Pyruvic acid
- Mitochondrial DNA analysis
Cerebrospinal fluid (CSF) analysis
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Other investigations
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Specific treatments
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Symptomatic treatments
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Supportive treatments
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Acronym
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References
- Fan HC, Lee HF, Yue CT, Chi CS. Clinical characteristics of mitochondrial encephalomyopathy, lactic acidosis, and stroke-like episodes. Life (Basel) 2021; 11:1111.
- Finsterer J, Aliyev R. Metabolic stroke or stroke-like lesion: peculiarities of a phenomenon. J Neurol Sci 2020; 412:116726.
- Finsterer J. Mitochondrial metabolic stroke: phenotype and genetics of stroke-like episodes. J Neurol Sci 2019; 400:135-141.
- Finsterer J. Therapeutic management of stroke-like episodes varies from that of encephalitis. Medicine (Baltimore) 2020; 99:e19141.
- Martinez-Fernandez E, Gil-Peralta A, Garcia-Lozano R, et al. Mitochondrial disease and stroke. Stroke 2001; 32:2507-2510.
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