Langerhans cell histiocytosis (LCH): treatment
Written and reviewed by Dr Ibrahim Imam, Consultant Neurologist. Last reviewed .
Langerhans cell histiocytosis (LCH): treatment. Topical steroids, Topical tacrolimus, Topical nitrogen mustard. Fully referenced neurology checklist.
Treatment of skin lesions
- Topical steroids
- Topical tacrolimus
- Topical nitrogen mustard
- Topical PUVA
- Oral methotrexate
- Oral hydroxyurea
- Thalidomide
Treatment of single organ lung lesions
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Treatment of multifocal bone lesions
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Treatment of multifocal skin lesions
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Treatment of multi-organ disease
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Treatment of neurodegenerative symptoms
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Other treatments
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Investigational treatments
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Treatments to avoid
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Synonym
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References
- Satter EK, High WA. Langerhans cell histiocytosis: a review of the current recommendations of the Histiocyte Society. Pediatr Dermatol 2008; 25:291-295.
- Leung AKC, Lam JM, Leong KF. Childhood Langerhans cell histiocytosis: a disease with many faces. World J Pediatr 2019; 15:536-545.
- Girschikofsky M, Arico M, Castillo D, et al. Management of adult patients with Langerhans cell histiocytosis: recommendations from an expert panel on behalf of Euro-Histio-Net.Orphanet J Rare Dis 2013; 8:72.
- Goyal G, Tazi A, Go RS, et al. International expert consensus recommendations for the diagnosis and treatment of Langerhans cell histiocytosis in adults. Blood 2022; 139:2601-2621.
- Donadieu J, Chalard F, Jeziorski E. Medical management of Langerhans cell histiocytosis from diagnosis to treatment. Expert Opin Pharmacother 2012; 13:1309-1322.
