Langerhans cell histiocytosis (LCH): clinical features
Written and reviewed by Dr Ibrahim Imam, Consultant Neurologist. Last reviewed .
Langerhans cell histiocytosis (LCH): clinical features. Eosinophilic granuloma: unifocal LCH. Fully referenced neurology checklist.
Subtypes
- Eosinophilic granuloma: unifocal LCH
- Hand-Schuller-Christian disease: multifocal unisystem LCH
- Letterer-Siwe disease: disseminated multifocal multisystem LCH
Systemic symptoms
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Lung features
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Lung features
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Dental features
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Gastrointestinal features
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Haematological features
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Skeletal features
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Cutaneous features
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Nail features
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Ophthalmic features
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Neurological features
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Synonym
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References
- Satter EK, High WA. Langerhans cell histiocytosis: a review of the current recommendations of the Histiocyte Society. Pediatr Dermatol 2008; 25:291-295.
- Leung AKC, Lam JM, Leong KF. Childhood Langerhans cell histiocytosis: a disease with many faces. World J Pediatr 2019; 15:536-545.
- Girschikofsky M, Arico M, Castillo D, et al. Management of adult patients with Langerhans cell histiocytosis: recommendations from an expert panel on behalf of Euro-Histio-Net.Orphanet J Rare Dis 2013; 8:72.
- Harmon CM, Brown N. Langerhans cell histiocytosis: a clinicopathologic review and molecular pathogenetic update. Arch Pathol Lab Med 2015; 139:1211-1214.
- Lian C, Lu Y, Shen S. Langerhans cell histiocytosis in adults: a case report and review of the literature. Oncotarget 2016; 7:18678-18683.
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