Inclusion body myositis (IBM): treatment
Written and reviewed by Dr Ibrahim Imam, Consultant Neurologist. Last reviewed .
Inclusion body myositis (IBM): treatment. Exercise programme, Botulinum toxin: for dysphagia. Fully referenced neurology checklist.
Treatment
- Exercise programme
- Botulinum toxin: for dysphagia
- Cricopharyngeal myotomy: for dysphagia
- Orthoses
- Tendon transfers
- CoQ10 to enhance endurance
Treatment considerations in severe disease
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Investigational treatments
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Emerging investigation
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References
- Solorzano GE, Phillips LH. Inclusion body myositis: diagnosis, pathogenesis, and treatment options. Rheum Dis Clin N Am 2011; 37:173-183.
- Dalakas MC. Therapeutic advances and future prospects in immune-mediated inflammatory myopathies. Ther Adv Neurol Disord 2008; 1:157-166.
- Lucchini M, Maggi L, Pegoraro E, et al. Anti-cN1A antibodies are associated with more severe dysphagia in sporadic inclusion body myositis. Cells 2021; 10:1146.
- Lilleker JB. Advances in the early diagnosis and therapy of inclusion body myositis. Curr Opin Rheumatol 2018; 30:644-649.
- Noto YI, Kondo M, Tsuji Y, et al. Diagnostic value of muscle [11C] PIB-PET in inclusion body myositis. Front Neurol 2020; 10:1386.
