Hodgkin’s lymphoma: neurological features

Written and reviewed by Dr Ibrahim Imam, Consultant Neurologist. Last reviewed .

Hodgkin’s lymphoma: neurological features. Transient ischaemic attacks (TIAs), Stroke. Fully referenced neurology checklist.

Parenchymal features

  • Transient ischaemic attacks (TIAs)
  • Stroke
  • Cardioembolism: from cardiomyopathy
  • Cranial nerve palsies
  • Headache
  • Weakness
  • Papilloedema
  • Seizures
  • Cavernous sinus syndrome

Leptomeningeal features

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Spinal cord features

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Central paraneoplastic features

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Peripheral paraneoplastic features

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Frequent paraneoplastic antibodies

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Radiotherapy-related features

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Chemotherapy-related features

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References

  1. Grimm S, Chamberlain M. Hodgkin’s lymphoma: a review of neurologic complications. Adv Hematol 2011; 2011:624578.
  2. van Blydenstein SA, Patel M, Philip V, et al. Classical Hodgkin Lymphoma involving the central nervous system (brain) - an unusual presentation. Clin Case Rep 2014; 2:88-92.
  3. Kasner SE, Galetta SL, Vaughn DJ. Cavernous sinus syndrome in Hodgkin's disease. J Neuroophthalmol 1996; 16:204-207.
  4. Alioglu B, Ustun H, Sonmez A, Kaplan H, Arikan FI, Dallar Y. A rare presentation of central nervous system in a pediatric patient with Hodgkin disease: cavernous sinus syndrome. J Pediatr Hematol Oncol 2009; 31:774-777.
  5. Forest KA, Hemmer AM, Stacy Md K. Thoracic myelopathy in a teenager caused by stage IV Hodgkin's lymphoma. Cureus 2023; 15:e38298.
  6. And 23 more. Subscribe to see the full list

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