HIV associated neurocognitive disorders (HAND): clinical features

Written and reviewed by Dr Ibrahim Imam, Consultant Neurologist. Last reviewed .

HIV associated neurocognitive disorders (HAND): clinical features. Asymptomatic neurocognitive impairment (ANI). Fully referenced neurology checklist.

Classification

  • Asymptomatic neurocognitive impairment (ANI)
  • Mild neurocognitive disorder (MND)
  • HIV associated dementia (HAD):

HIV-associated dementia (HAD)

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Infective differential diagnoses

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Other differential diagnoses

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Neurocognitive screening tools

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Neurocognitive testing

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References

  1. Eggers C, Arendt G, Hahn K, et al; German Association of Neuro-AIDS und Neuro-Infectiology (DGNANI). HIV-1-associated neurocognitive disorder: epidemiology, pathogenesis, diagnosis, and treatment. J Neurol 2017; 264:1715-1727. 
  2. Sacktor N. Changing clinical phenotypes of HIV-associated neurocognitive disorders. J Neurovirol 2017; doi: 10.1007/s13365-017-0556-6 (Epub ahead of print).
  3. Carroll A, Brew B. HIV-associated neurocognitive disorders: recent advances in pathogenesis, biomarkers, and treatment. F1000Res 2017; 6:312.
  4. Vera JH, Ridha B, Gilleece Y, Amlani A, Thorburn P, Dizdarevic S. PET brain imaging in HIV-associated neurocognitive disorders (HAND) in the era of combination antiretroviral therapy. Eur J Nucl Med Mol Imaging 2017; 44:895-902. 

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